Educational guide
Customize Your Own Peptide Pool!
Customize Your Own Peptide Pool! Published on 12/12/2024 Custom PepMix™ Peptide Pools can be tailored to your exact specifications and application, offering unparalleled precision and flexibility. Here is what we bring to the table: Key Features: A variety of
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Customize Your Own Peptide Pool!
Published on 12/12/2024
Custom PepMix™ Peptide Pools can be tailored to your exact specifications and application, offering unparalleled precision and flexibility.
Here is what we bring to the table:
Key Features:
A variety of quality grades, backed by rigorous quality management.
In silico design tools for optimized performance. We are here to help!
Packaging and aliquotation in tubes, plates, PepSup™ formulations, or even your own tubes — all prepared in an ISO8 clean room environment.
Optional Analysis such as stability testing, endotoxin and sterility testing, and many more
Small scale (5-20 µg/peptide) and large scale (1mg/peptide or more) options
Post-translational modifications (PTMs)
Applications:
Custom PepMix™ peptide pools are ideal for antigen-specific T-cell stimulation in T-cell assays (e.g. in ELISpot, cytokine staining, cell-mediated cytotoxicity or proliferation assays) in
Basic Research
Regulated Research (GLP studies)
Clinical Development As critical raw materials
Quality Grades:
Research Grade: Micro-scale, unpurified, fast delivery and low cost
Development Grade: flexible scales starting from 1mg upwards, purity at 70%-90, each peptide is analyzed via HPLC
Trial Grade: flexible scales starting from 1mg upwards, purity at 90%-95%, each peptide is analyzed via HPLC, further analyis services optional
Pool Formats:
Overlapping peptide pools to represent an entire protein
Selected epitope pools to combine multiple immunodominant epitopes
Matrix pools for efficient epitope mapping
ULTRA pools for ultimate coverage of natural sequence variants
Individual peptide aliquots
Benefits of Custom PepMix™ Pools:
The individual peptides are quality controlled and guaranteed for identity and purity CoA and HPLC-MS data available for each individual peptide batch
No false positive T-cell responses due to contaminating deletion peptides
No toxic inhibition of T-cell responses due to stringent purification of each peptide
Minimization of endotoxin contamination due to low bioburden process
ADCF policy
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