Educational guide
Custom PepMix™ Peptide Pools | JPT
Custom PepMix™ Peptide Pools PepMix™ Peptide Pools are extremely efficient for Antigen-specific T-cell stimulation in T cell assays (e.g. in ELISpot, cytokine staining, cell-mediated cytotoxicity or proliferation assays) In-vitro T-cell expansion Dendritic cel
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Custom PepMix™ Peptide Pools
PepMix™ Peptide Pools are extremely efficient for
Antigen-specific T-cell stimulation in T cell assays (e.g. in ELISpot, cytokine staining, cell-mediated cytotoxicity or proliferation assays)
In-vitro T-cell expansion
Dendritic cell pulsing
Immune monitoring
Cellular immune response profiling
T-cell epitope identification
Standardization of T-cell assays
PepMix™ Peptide Pools are the best because
Produced under stringent quality management
Each peptide quality controlled and guaranteed for identity and purity
CoA and HPLC-MS data available for each individual peptide batch
High batch-to-batch consistency
No false positive T-cell responses by contaminating deletion peptides
No toxic inhibition of T-cell responses due to stringent purification of each peptide
Minimization of endotoxin contamination due to low bioburden process
ADCF policy in place
HLA independent stimulation (for antigen spanning peptide pools)
Order Your Custom PepMix™ Peptide Pool
Order Individual ELISpot Peptides
ELISpot Service
In silico peptide design to avoid potential synthesis and application difficulties from the outset
Selecting the appropriate purity, quantity and specfications to meet your needs
Designing the most meaningful experiment in close consultation with the customer
Performing the experiment according to our standards, which are harmonized and validated by Proficiency Panel guidelines and SOPs
Professional data analysis , reporting and discussion of data
We also offer troubleshooting support and method development services
Applications
Applications for Custom PepMix™ Peptide Pools
Antigen-specific stimulation of T-cells
Immune monitoring during diseases or therapy
Assessment of vaccine efficacy
Evaluation of neo epitopes
Identification of the best antigen for individual patients (PepMix™ Collections)
Application Notes for Peptide Pools
Benefits
Benefits of Custom PepMix™ Peptide Pools
Overlapping peptide pools are preferable to whole proteins for antigen-specific T-cell stimulation because:
Simultaneous detection of CD4+ and CD8+ responses in a single sample Equivalent or better stimulation T-cell responses compared to whole protein antigens
Antigen spanning peptide pools stimulate T-cells in an HLA independent manner
All epitopes covered, epitope spreading addressed
Purified peptide pools eliminate risk of toxic inhibition of T-cell responses
No false positive T-cell stimulation caused by deletion peptides
Superior control compared to phytohemagglutinin (PHA) and concanavalin A (ConA)
Improved responses in stored blood and PBM cells compared to whole proteins
High-batch-to-batch reproducibility
Reliable chemical and biochemical quality control and quality assurance for peptide synthesis and peptide pool generation
Prolonged shelf stability when stored freeze dried
Testimonials
Testimonials for Custom PepMix™ Peptide Pools
References
References for Custom PepMix™ Peptide Pools
Read References with PepMix™ Peptide Pools - Controls Pools
Read References with PepMix™ Peptide Pools for Infectious Diseases
Read References with PepMix™ Peptide Pools for Tumor Associated Antigens
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