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Biologique Recherche Lotion P50 Versus Medik8 Press And Glow Tonic

Biologique Recherche Lotion P50 Versus Medik8 Press And Glow Tonic This smoothing toner is formulated around Gluconolactone and Lactic Acid to refine skin texture and refine the look of pores. This smoothing toner is formulated around Gluconolactone to refine

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Biologique Recherche Lotion P50 Versus Medik8 Press And Glow Tonic

This smoothing toner is formulated around Gluconolactone and Lactic Acid to refine skin texture and refine the look of pores.

This smoothing toner is formulated around Gluconolactone to refine skin texture and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Gluconolactone

Lactic Acid

Glycerin

Propylene Glycol

Niacinamide

Citric Acid

Ethoxydiglycol

Magnesium Chloride

Malic Acid

Vinegar

Phytic Acid

Salicylic Acid

Cochlearia Armoracia Root Extract

Arctium Lappa Root Extract

Rumex Acetosa Leaf Extract

Myrtus Communis Extract

Commiphora Myrrha Resin Extract

Allium Cepa Bulb Extract

Thymus Vulgaris Flower/Leaf Oil

Sulfur

Sorbitol

Phenoxyethanol

Sodium Benzoate

Potassium Sorbate

Water, Gluconolactone, Lactic Acid, Glycerin, Propylene Glycol, Niacinamide, Citric Acid, Ethoxydiglycol, Magnesium Chloride, Malic Acid, Vinegar, Phytic Acid, Salicylic Acid, Cochlearia Armoracia Root Extract, Arctium Lappa Root Extract, Rumex Acetosa Leaf Extract, Myrtus Communis Extract, Commiphora Myrrha Resin Extract, Allium Cepa Bulb Extract, Thymus Vulgaris Flower/Leaf Oil, Sulfur, Sorbitol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Hydrolyzed Opuntia Ficus-Indica Flower Extract

Euterpe Oleracea Fruit Extract

Aloe Barbadensis Leaf Juice

Sodium Hydroxide

Sodium Citrate

Hydroxyacetophenone

Ethylhexylglycerin

Water, Gluconolactone, Glycerin, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Euterpe Oleracea Fruit Extract, Aloe Barbadensis Leaf Juice, Sodium Hydroxide, Sodium Citrate, Hydroxyacetophenone, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Sodium Benzoate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Gluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.

When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.

PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.

Gluconolactone has some interesting properties:

In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.

This ingredient is is an created by reacting gluconic acid with an alcohol.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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