Biologique Recherche Crème VIP O2 Oxygenating and Anti-Pollution Cream Versus Biologique Recherche Crème Iso-Placenta Regenerating Face Cream

Biologique Recherche Crème VIP O2 Oxygenating and Anti-Pollution Cream Versus Biologique Recherche Crème Iso-Placenta Regenerating Face Cream

This moisturizer is formulated around Saccharide Isomerate to hydrate skin.

This smoothing moisturizer is formulated around Niacinamide and Centella Asiatica Extract to refine skin texture and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Stearic Acid

Propylene Glycol

Glycerin

Palmitic Acid

Cetyl Alcohol

Pentylene Glycol

Polysorbate 40

PEG-2 Stearate

Tea-Stearate

Perfluorodecalin

Saccharide Isomerate

Taraxacum Officinale Rhizome/Root Extract

Hydrolyzed Candida Saitoana Extract

Yeast Extract

Sodium Hyaluronate

Citric Acid

Polyperfluoromethylisopropyl Ether

Poloxamer 188

Caprylyl Glycol

P-Anisic Acid

Phenoxyethanol

Ethylhexylglycerin

Sodium Citrate

Sodium Benzoate

Water, Stearic Acid, Propylene Glycol, Glycerin, Palmitic Acid, Cetyl Alcohol, Pentylene Glycol, Polysorbate 40, PEG-2 Stearate, Tea-Stearate, Perfluorodecalin, Saccharide Isomerate, Taraxacum Officinale Rhizome/Root Extract, Hydrolyzed Candida Saitoana Extract, Yeast Extract, Sodium Hyaluronate, Citric Acid, Polyperfluoromethylisopropyl Ether, Poloxamer 188, Caprylyl Glycol, P-Anisic Acid, Phenoxyethanol, Ethylhexylglycerin, Sodium Citrate, Sodium Benzoate

Dicaprylyl Carbonate

Sucrose Polystearate

C10-18 Triglycerides

1,2-Hexanediol

Niacinamide

Passiflora Edulis Seed Oil

Polyamide-5

Betula Alba Bark Extract

Equisetum Arvense Extract

Hedera Helix Leaf/Stem Extract

Fucus Vesiculosus Extract

Centella Asiatica Extract

Glycine Soja Oil

Bacillus/Soybean Ferment Extract

Hexapeptide-11

Oligopeptide-1

Oligopeptide-2

Oligopeptide-3

Ascorbyl Glucoside

Acetyl Glutamine

Folic Acid

Lecithin

Tocopherol

Sodium Stearoyl Glutamate

Butylene Glycol

Hydrogenated Polyisobutene

Polyacrylate Crosspolymer-6

T-Butyl Alcohol

Water, Propylene Glycol, Dicaprylyl Carbonate, Glycerin, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Passiflora Edulis Seed Oil, Polyamide-5, Betula Alba Bark Extract, Equisetum Arvense Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Glycine Soja Oil, Yeast Extract, Bacillus/Soybean Ferment Extract, Hexapeptide-11, Oligopeptide-1, Oligopeptide-2, Oligopeptide-3, Ascorbyl Glucoside, Acetyl Glutamine, Folic Acid, Sodium Hyaluronate, Lecithin, Tocopherol, Sodium Stearoyl Glutamate, Butylene Glycol, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, T-Butyl Alcohol, Caprylyl Glycol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.

As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.

The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).

It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.

Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Yeast extract is a silky, clear liquid derived from yeast (usually Saccharomyces cerevisiae or Torula yeast).

This ingredient has plenty of skin benefits:

Bioferments of yeast and soy have been found to reduce hyperpigmentation at low levels.

Yeast extract is fungal acne safe because it's made up of amino acids, peptides, B vitamins, and nucleotides (not the C11-C24 fatty acids that Malassezia needs to thrive).

The "yeast" in the name can be misleading, but FA safety is about chemical composition and not ingredient origin.

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