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Anua Azelaic 10 Hyaluron Redness Soothing Pad Versus Nø Cosmetics No Make Up Shake Today Hypercalm 2-Phase Cloud Serum

Anua Azelaic 10 Hyaluron Redness Soothing Pad Versus Nø Cosmetics No Make Up Shake Today Hypercalm 2-Phase Cloud Serum This calming toner pad uses a pre-saturated pad with Panthenol and Sodium Hyaluronate to calm redness and hydrate skin. This calming serum is

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Anua Azelaic 10 Hyaluron Redness Soothing Pad Versus Nø Cosmetics No Make Up Shake Today Hypercalm 2-Phase Cloud Serum

This calming toner pad uses a pre-saturated pad with Panthenol and Sodium Hyaluronate to calm redness and hydrate skin.

This calming serum is formulated around Azelaic Acid and Ceramide NP to calm redness and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Dipropylene Glycol

Propanediol

Glycerin

Betaine

Diglycerin

Methylpropanediol

Hydroxyethyl Urea

1,2-Hexanediol

Hydroxyacetophenone

Glycereth-25 PCA Isostearate

Panthenol

Melia Azadirachta Leaf Extract

Xanthan Gum

Ethylhexylglycerin

Disodium EDTA

Melia Azadirachta Flower Extract

Allantoin

Sodium Polyacrylate

Glyceryl Acrylate/Acrylic Acid Copolymer

Pvm/Ma Copolymer

Theobroma Cacao Seed Extract

Dextrin

Hydrolyzed Hyaluronic Acid

Hyaluronic Acid

Sodium Hyaluronate

Azelaic Acid

Bisabolol

Dipotassium Glycyrrhizate

Zea Mays Kernel Extract

Centella Asiatica Extract

Centella Asiatica Leaf Extract

Centella Asiatica Root Extract

Asiatic Acid

Asiaticoside

Madecassic Acid

Madecassoside

Ceramide NP

Chlorella Vulgaris Extract

Melaleuca Alternifolia Leaf Water

Squalane

Dimethylsilanol Hyaluronate

Hydrolyzed Sodium Hyaluronate

Fructan

Pinus Pinaster Bark Extract

Potassium Hyaluronate

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Glucose

Sodium Hyaluronate Dimethylsilanol

Sodium Acetylated Hyaluronate

Water, Butylene Glycol, Dipropylene Glycol, Propanediol, Glycerin, Betaine, Diglycerin, Methylpropanediol, Hydroxyethyl Urea, 1,2-Hexanediol, Hydroxyacetophenone, Glycereth-25 PCA Isostearate, Panthenol, Melia Azadirachta Leaf Extract, Xanthan Gum, Ethylhexylglycerin, Disodium EDTA, Melia Azadirachta Flower Extract, Allantoin, Sodium Polyacrylate, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Theobroma Cacao Seed Extract, Dextrin, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate, Azelaic Acid, Bisabolol, Dipotassium Glycyrrhizate, Zea Mays Kernel Extract, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Asiatic Acid, Asiaticoside, Madecassic Acid, Madecassoside, Ceramide NP, Chlorella Vulgaris Extract, Melaleuca Alternifolia Leaf Water, Squalane, Dimethylsilanol Hyaluronate, Hydrolyzed Sodium Hyaluronate, Fructan, Pinus Pinaster Bark Extract, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Glucose, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate

Caprylic/Capric Triglyceride

C13-15 Alkane

Prunus Armeniaca Kernel Oil

Persea Gratissima Oil

Brassica Campestris Seed Oil

Simmondsia Chinensis Seed Oil

Stearalkonium Hectorite

Polygonum Tinctorium Leaf Extract

Solanum Lycopersicum Fruit Extract

Propylene Carbonate

Tocopherol

Rosmarinus Officinalis Leaf Extract

Helianthus Annuus Seed Oil

Caprylic/Capric Triglyceride, C13-15 Alkane, Prunus Armeniaca Kernel Oil, Azelaic Acid, Persea Gratissima Oil, Brassica Campestris Seed Oil, Simmondsia Chinensis Seed Oil, Stearalkonium Hectorite, Polygonum Tinctorium Leaf Extract, Squalane, Solanum Lycopersicum Fruit Extract, Ceramide NP, Propylene Carbonate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Seed Oil

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes it special?

OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.

Here's what each tier does best:

Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.

Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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