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Bioderma Sébium Hydra Versus Nø Cosmetics All-In Barrier Cream

Bioderma Sébium Hydra Versus Nø Cosmetics All-In Barrier Cream This barrier-repair moisturizer is formulated around Glycyrrhetinic Acid and Allantoin to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Butyrosp

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Bioderma Sébium Hydra Versus Nø Cosmetics All-In Barrier Cream

This barrier-repair moisturizer is formulated around Glycyrrhetinic Acid and Allantoin to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Panthenol to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Paraffinum Liquidum

Ethylhexyl Palmitate

Dipropylene Glycol

Xylitol

Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isohexadecane

Caprylic/Capric Triglyceride

Glycyrrhetinic Acid

Tocopheryl Acetate

Polysorbate 80

Disodium EDTA

Allantoin

Fructooligosaccharides

Mannitol

Propylene Glycol

Cetrimonium Bromide

Ceramide NP

Rhamnose

Ginkgo Biloba Leaf Extract

Dodecyl Gallate

Laminaria Ochroleuca Extract

Parfum

Water, Glycerin, Paraffinum Liquidum, Ethylhexyl Palmitate, Dipropylene Glycol, Xylitol, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Tocopheryl Acetate, Polysorbate 80, Disodium EDTA, Allantoin, Fructooligosaccharides, Mannitol, Propylene Glycol, Cetrimonium Bromide, Ceramide NP, Rhamnose, Ginkgo Biloba Leaf Extract, Dodecyl Gallate, Laminaria Ochroleuca Extract, Parfum

Butyrospermum Parkii Butter

Panthenol

Cetearyl Alcohol

Simmondsia Chinensis Seed Oil

Dicaprylyl Ether

Glyceryl Stearate

Prunus Armeniaca Kernel Oil

C13-15 Alkane

Propanediol

Pentylene Glycol

Cetearyl Olivate

Argania Spinosa Kernel Oil

Diglycerin

Ectoin

Ceramide EOP

Ceramide Ns

Ceramide As

Ceramide AP

Cholesterol

Hydrogenated Lecithin

Sucrose Distearate

Heterotheca Inuloides Flower Extract

Sorbitan Olivate

Sea Water

Laminaria Digitata Extract

Chlorella Vulgaris Extract

Saccharide Isomerate

Xanthan Gum

Hydroxyacetophenone

Phenoxyethanol

Ethylhexylglycerin

Lactic Acid

Citric Acid

Water, Butyrospermum Parkii Butter, Panthenol, Cetearyl Alcohol, Simmondsia Chinensis Seed Oil, Dicaprylyl Ether, Glycerin, Glyceryl Stearate, Prunus Armeniaca Kernel Oil, C13-15 Alkane, Propanediol, Pentylene Glycol, Cetearyl Olivate, Argania Spinosa Kernel Oil, Diglycerin, Ectoin, Ceramide EOP, Ceramide Ns, Ceramide NP, Ceramide As, Ceramide AP, Cholesterol, Hydrogenated Lecithin, Sucrose Distearate, Heterotheca Inuloides Flower Extract, Dipropylene Glycol, Sorbitan Olivate, Sea Water, Laminaria Digitata Extract, Chlorella Vulgaris Extract, Saccharide Isomerate, Xanthan Gum, Hydroxyacetophenone, Phenoxyethanol, Ethylhexylglycerin, Lactic Acid, Citric Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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