is nurtec a peptide FAQ

Nurtec ODT (rimegepant) is commonly used for the following conditions.

Nurtec ODT interacts with grapefruit. While taking Nurtec ODT, do not eat or drink any grapefruit products, including grapefruit, grapefruit juice, or any juices that contain grapefruit. There are no known interactions between Nurtec ODT and alcohol. However, alcohol can trigger migraine attacks in some people. Consult your healthcare provider for more information and medical advice.

If you or someone else has used too much Nurtec ODT, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

Yes. When using Nurtec ODT, it’s important to keep track of your doses and how your treatment is going. This can help you avoid taking more than the recommended amount. Tracking your Nurtec ODT treatment can also help you and your doctor understand whether your migraine treatment plan is working. To do this, use a notebook or the notes or calendar app on your phone. Write down things such as:

Nurtec ODT belongs to a class of drugs called calcitonin gene-related peptide (CGRP) receptor antagonists. CGRP receptor antagonists that are taken by mouth, such as Nurtec ODT, are also called gepants. CGRP is a protein in your brain that’s thought to be involved in causing migraine symptoms. Nurtec ODT works to block CGRP receptors in the brain. This prevents CGRP from attaching to those receptors, which can prevent it from causing migraine symptoms. For more details, see the “How Nurtec ODT works” section above.

Whether you take Nurtec ODT to treat or help prevent migraine episodes, you might take it over a long period. If you and your doctor decide that Nurtec ODT is safe and effective for you, you’ll likely take it long term, since migraine is often a long lasting condition. Nurtec ODT is approved for:

Yes, Nurtec ODT can be prescribed to help prevent migraine symptoms due to episodic migraine. It can also be prescribed for you to take as needed for acute (immediate) treatment of migraine symptoms. See the “Nurtec ODT use for migraine” section above for details. If you have questions about migraine prevention, talk with your doctor. It’s usually safe to drink alcohol while taking Nurtec ODT. However, it’s important to note that alcohol may trigger migraine episodes, which Nurtec ODT is approved to treat and help prevent. Also, alcohol can harm your liver. And certain drugs used for migraine that contain acetaminophen can harm your liver, too. Drinking alcohol while using these treatments can increase your risk of liver damage. For this reason, you should avoid alcohol if you regularly take migraine drugs that contain acetaminophen. If you drink alcohol, ask your doctor how much is safe for you to drink, given your condition and treatment plan. You should take Nurtec ODT according to your doctor’s or another healthcare professional’s instructions. If you have questions, talk with your doctor or pharmacist, or check Nurtec ODT’s prescribing information. Nurtec ODT comes as a tablet that you take by mouth. It can be taken either:

No, Nurtec ODT isn’t approved to treat cluster headaches. It’s only approved for prevention of migraine symptoms due to episodic migraine and acute (immediate) treatment of migraine episodes with or without an aura. (An aura refers to unusual symptoms or sensations that can occur before a migraine episode.) Cluster headaches and migraine can both cause headache pain. But cluster headaches can cause different symptoms from migraine, and they may last longer. If you have cluster headache episodes that aren’t managed, talk with your doctor. They may recommend a drug that’s approved to treat cluster headaches, such as galcanezumab-gnlm (Emgality).

When taken as directed, Nurtec ODT is fully absorbed by the body in about 1.5 hours. In a clinical trial, 2 hours after taking Nurtec ODT for acute (immediate) migraine treatment, many people had reduced or no migraine pain and were able to function as usual. Also, some people continued to experience relief from migraine symptoms for 48 hours after taking Nurtec ODT. In another clinical trial, people taking Nurtec ODT for migraine prevention reported a reduction in the number of days per month that they had migraine symptoms. Starting in their first month of Nurtec ODT treatment, they experienced fewer days with migraine symptoms than they had before starting the treatment. Nurtec ODT’s half-life is 11 hours. This is the time it takes your body to clear half of the drug. Most drugs are cleared from the body after about five half-lives. So it would take about 55 hours (just over 2 days) for your body to clear Nurtec ODT from its system. If you can become pregnant, are breastfeeding, or are using birth control, it’s important to consider whether Nurtec ODT is a safe choice for you. You can refer to this article for more information, including details about a Nurtec ODT pregnancy registry you may join. (A pregnancy registry collects information about the safety of specific medications during pregnancy.) If you have additional questions, talk with your doctor. Here are answers to some frequently asked questions about Nurtec ODT.

No. You should not crush, split, or chew Nurtec ODT tablets. To make sure Nurtec ODT works as intended, you should keep the tablets in their original blister packaging until you need to take a dose. To remove a tablet from the packaging, use clean, dry hands to carefully peel off the foil from each blister. Don’t push the tablets through the foil because doing so may break them. Before taking Nurtec ODT, talk with your doctor about your health history. Nurtec ODT may not be right for you if you have certain medical conditions or other factors affecting your health. These include: