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Wolverine Stack Research Protocols: Comparison

Sequential Titration (8-week) 300mcg daily × 10 days, then 600mcg AM 250mcg added week 2, split AM/PM 5mL IM on days 1, 4, 7 of weeks 4–8 BDNF at weeks 0/3/6, digit span weekly, cortisol reactivity at baseline/week 4/week 8 Gold standard for isolating individu

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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • Sequential Titration (8-week)
  • 300mcg daily × 10 days, then 600mcg AM
  • 250mcg added week 2, split AM/PM
  • 5mL IM on days 1, 4, 7 of weeks 4–8
  • BDNF at weeks 0/3/6, digit span weekly, cortisol reactivity at baseline/week 4/week 8
  • Gold standard for isolating individual compound effects. Longest timeline, highest compliance burden
  • Simultaneous Loading (4-week)
  • 600mcg AM from day 1
  • 500mcg AM from day 1
  • 10mL IV twice weekly entire protocol
  • Subjective mood scales, n-back testing weekly
  • Higher dropout rate (35%) due to overstimulation; difficult to attribute effects to specific compounds
  • Semax-Focused (6-week)
  • 600mcg AM daily, full protocol
  • None
  • Working memory, processing speed, BDNF at weeks 0/3/6
  • Cleanest data on Semax alone. No synergy effects, serves as single-agent control
  • Selank-Focused Anxiolytic (4-week)
  • 750mcg split AM/noon
  • Cortisol sampling, HRV monitoring, subjective anxiety scales
  • Isolates stress modulation without confounding neuroplasticity variables
  • Maintenance Micro-Dose (12-week)
  • 300mcg 5 days/week
  • 250mcg 5 days/week
  • 5mL IM once every 10 days
  • Quarterly BDNF, monthly cognitive testing
  • Mimics long-term use patterns. Lower peak effects, potentially sustainable