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What Can Preclinical Evidence Show Versus Clinical Outcomes?
Preclinical evidence can show whether a compound changes a marker, cell behavior, protein expression, or tissue-culture response under controlled conditions. It cannot show whether a person will experience better cardiac function, fewer symptoms, lower heart f
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- Preclinical evidence can show whether a compound changes a marker, cell behavior, protein expression, or tissue-culture response under controlled conditions. It cannot show whether a person will experience better cardiac function, fewer symptoms, lower heart failure hospitalization rates, or improved survival [14] [16].