Understand the source comparison
TB-4 Research Memory Considerations: Full Comparison
Pre-reconstitution (lyophilised) −20°C, desiccated 12–24 months Moisture absorption, oxidation Gold standard. Minimal risk if sealed properly Post-reconstitution (aqueous) 2–8°C 14–28 days (bacteriostatic water) Proteolysis, aggregation, oxidation High-risk ph
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Pre-reconstitution (lyophilised)
- −20°C, desiccated
- 12–24 months
- Moisture absorption, oxidation
- Gold standard. Minimal risk if sealed properly
- Post-reconstitution (aqueous)
- 2–8°C
- 14–28 days (bacteriostatic water)
- Proteolysis, aggregation, oxidation
- High-risk phase. Aliquot immediately, use quickly
- Frozen aliquots (−80°C)
- −80°C
- 3–6 months (single freeze only)
- Ice crystal shear stress
- Acceptable for long studies if no refreeze occurs
- Room temperature (reconstituted)
- 20–25°C
- 48–72 hours before major loss
- Rapid oxidation, aggregation
- Unacceptable except during active use (<4 hours)
- Shipping (reconstituted)
- 2–8°C maintained
- 24–36 hours (validated shipper)
- Thermal excursion, mechanical agitation
- Very high risk. Avoid unless no alternative exists