Understand the source comparison
TB-4 Research Body Recomp Considerations: Comparison
TB-4 (Thymosin Beta-4) Actin polymerisation, angiogenesis, anti-inflammatory signaling Skeletal muscle, connective tissue, cardiovascular tissue Accelerates recovery and sustains training volume during caloric deficits. Indirect recomp support 2–3x weekly (2–5
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- TB-4 (Thymosin Beta-4)
- Actin polymerisation, angiogenesis, anti-inflammatory signaling
- Skeletal muscle, connective tissue, cardiovascular tissue
- Accelerates recovery and sustains training volume during caloric deficits. Indirect recomp support
- 2–3x weekly (2–5mg per dose)
- Best for recovery bottleneck removal; doesn't stimulate muscle growth directly but allows higher sustained volume
- BPC-157
- Angiogenesis, collagen synthesis, nitric oxide pathway modulation
- Tendons, ligaments, gastrointestinal tissue, muscle
- Injury recovery and tissue repair. Supports joint health during high-volume training
- Daily (250–500mcg per dose)
- Overlaps with TB-4 in mechanism; stack cautiously or alternate protocols
- CJC-1295 / Ipamorelin
- Growth hormone secretagogue. Stimulates pulsatile GH release
- Pituitary gland (upstream effect on all tissues)
- Direct anabolic signaling; increases protein synthesis and lipolysis
- 3–5x weekly (100–200mcg each compound)
- TB-4 synergises well here. GH stimulates growth, TB-4 removes recovery limitation
- GLP-1 Agonists (Semaglutide, Tirzepatide)
- Appetite suppression, insulin sensitisation, gastric emptying delay
- Hypothalamus, pancreas, gastrointestinal tract
- Caloric deficit creation and metabolic health during fat loss phase
- Weekly (dose-dependent on compound)
- Critical for appetite control in deficit; TB-4 helps maintain lean mass GLP-1 use would otherwise compromise at high deficits
- Testosterone (research-grade analogs)
- Androgen receptor activation. Direct protein synthesis and nitrogen retention
- Skeletal muscle, bone, adipose tissue
- Direct anabolic effect; gold standard for lean mass gain in surplus or maintenance
- Varies by ester (daily to bi-weekly)
- TB-4 is complementary, not competitive; testosterone builds, TB-4 allows recovery to support the volume required