Understand the source comparison
TB-4 Need Refrigeration Storage: Handling Comparison
Lyophilised (pre-reconstitution) −20°C (freezer) 12–24 months 40–60% degradation over 18 months at room temp Reconstituted (in bacteriostatic water) 2–8°C (refrigerator) 28 days 50% potency loss within 48 hours at 25°C During shipping (lyophilised) Cold chain
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Lyophilised (pre-reconstitution)
- −20°C (freezer)
- 12–24 months
- 40–60% degradation over 18 months at room temp
- Reconstituted (in bacteriostatic water)
- 2–8°C (refrigerator)
- 28 days
- 50% potency loss within 48 hours at 25°C
- During shipping (lyophilised)
- Cold chain with gel packs
- 48–72 hours transit
- Temperature excursions above 25°C for >6 hours trigger degradation
- Aliquoted doses (reconstituted)
- 2–8°C, single-use vials
- 28 days from reconstitution date
- Each freeze-thaw cycle reduces activity 20–30%