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Peptide Therapy GuideClear peptide education

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Subcutaneous vs Intramuscular Pre-Workout Injection

Subcutaneous administration (into adipose tissue, typically the abdomen or thigh) provides slower, sustained release. Peptides diffuse into systemic circulation over 45–90 minutes. Intramuscular injection delivers faster uptake but higher local concentration,

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  • Subcutaneous administration (into adipose tissue, typically the abdomen or thigh) provides slower, sustained release. Peptides diffuse into systemic circulation over 45–90 minutes. Intramuscular injection delivers faster uptake but higher local concentration, which matters for site-specific injuries. Research professionals studying localised tissue repair often use IM injection within 2–3 inches of the injury site to maximise local peptide concentration during the workout window, though this requires precise anatomical knowledge and sterile technique beyond what most athletes possess. Our team's general recommendation: subcutaneous BPC-157 (250–500mcg) 30 minutes pre-workout for systemic tissue support, with IM reserved for targeted rehab protocols under professional supervision.