Understand the source comparison
Structural Comparison: MT-2 vs. Native α-MSH
Length 13 amino acids 7 amino acids Conformation Linear Cyclic (lactam bridge) Met at position 4 Yes (oxidation-susceptible) Replaced by Nle Phe stereochemistry L-Phe D-Phe (inverted) Terminal modifications None N-Ac / C-amide Metabolic stability Low High Rece
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Length
- 13 amino acids
- 7 amino acids
- Conformation
- Linear
- Cyclic (lactam bridge)
- Met at position 4
- Yes (oxidation-susceptible)
- Replaced by Nle
- Phe stereochemistry
- L-Phe
- D-Phe (inverted)
- Terminal modifications
- None
- N-Ac / C-amide
- Metabolic stability
- Low
- High
- Receptor selectivity
- Primarily MC1R
- MC1R, MC3R, MC4R, MC5R