Sesderma Azelac RU Liposomal Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

Sesderma Azelac RU Liposomal Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum Detailed comparison of Sesderma Azelac RU Liposomal Serum versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum. This brightening serum is formulated around 4-Butylresorcinol and Retinol to fade the look of dark spots and brighten dull-looking skin. This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles. Water Propylene Glycol Lecithin Alcohol Polymethyl Methacrylate PEG-40 Hydrogenated Castor Oil 4-Butylresorcinol Ascorbyl Glucoside Retinol Azelaic Acid Niacin Undecylenoyl Phenylalanine Glycyrrhetinic Acid Morus Alba Root Extract Diacetyl Boldine PEG/PPG-20/6 Dimethicone Sodium Cholate Polysorbate 20 Xanthan Gum Carbomer Triethanolamine Tocopheryl Acetate BHT Sodium Hydroxide Caprylic/Capric Triglyceride Sodium Chloride Hydroxypropyl Cyclodextrin BHA Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Triisopropanolamine Hydrochloric Acid Phenoxyethanol Ethylhexylglycerin Parfum Citronellyl Methylcrotonate Citral Coumarin Eugenol Limonene Isoeugenol Water, Propylene Glycol, Lecithin, Alcohol, Polymethyl Methacrylate, PEG-40 Hydrogenated Castor Oil, 4-Butylresorcinol, Ascorbyl Glucoside, Retinol, Azelaic Acid, Niacin, Undecylenoyl Phenylalanine, Glycyrrhetinic Acid, Morus Alba Root Extract, Diacetyl Boldine, PEG/PPG-20/6 Dimethicone, Sodium Cholate, Polysorbate 20, Xanthan Gum, Carbomer, Triethanolamine, Tocopheryl Acetate, BHT, Sodium Hydroxide, Caprylic/Capric Triglyceride, Sodium Chloride, Hydroxypropyl Cyclodextrin, BHA, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Triisopropanolamine, Hydrochloric Acid, Phenoxyethanol, Ethylhexylglycerin, Parfum, Citronellyl Methylcrotonate, Citral, Coumarin, Eugenol, Limonene, Isoeugenol Bifida Ferment Lysate PEG-8 Propanediol Bis-PEG-18 Methyl Ether Dimethyl Silane Methyl Gluceth-20 Glycereth-26 PEG-75 Butylene Glycol Adansonia Digitata Seed Extract Tripeptide-32 Sodium Hyaluronate Faex Extract Lactobacillus Ferment Cola Acuminata Seed Extract Anthemis Nobilis Flower Extract Hydrolyzed Algin Pantethine Caffeine Sodium Rna Bisabolol Squalane Glycerin Oleth-3 Phosphate Caprylyl Glycol Oleth-3 Oleth-5 Choleth-24 Hydrogenated Lecithin Jojoba Wax PEG-120 Esters Ceteth-24 Tetrasodium EDTA Potassium Sorbate Disodium EDTA CI 14700 CI 19140 Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. BHT is a synthetic antioxidant and preservative. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells. As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation. The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU. However, it was recently restricted for use in the UK as of April 2024. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And des