Understand the source comparison
Sermorelin Real vs Fake: Verification Method Comparison
Visual Inspection (Lyophilised Powder) Physical appearance and particle morphology White to off-white uniform crystalline powder, no clumping Yellow/brown discoloration, clumping, non-uniform texture First-line reject signal. Discoloration = oxidative degradat
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Visual Inspection (Lyophilised Powder)
- Physical appearance and particle morphology
- White to off-white uniform crystalline powder, no clumping
- Yellow/brown discoloration, clumping, non-uniform texture
- First-line reject signal. Discoloration = oxidative degradation or heat exposure
- Reconstitution Test
- Solubility and dissolution behavior
- Complete dissolution in bacteriostatic water within 60–90 seconds, clear colorless solution
- Cloudiness, particulate matter, incomplete dissolution after 2+ minutes
- Immediate functional test. Poor solubility suggests impurity or substitution
- HPLC Purity Analysis
- Separation and quantification of peptide vs impurities
- ≥98% purity with single dominant peak on chromatogram
- Multiple impurity peaks, purity <95%, chromatogram missing from CoA
- Gold standard for purity. No chromatogram = unverifiable claim
- Mass Spectrometry (MS)
- Molecular weight and amino-acid sequence confirmation
- Dominant peak at exactly 3357.96 Da (sermorelin acetate molecular weight)
- Peak at incorrect mass (3100 Da, 3500 Da), multiple peaks, no MS data provided
- Confirms molecular identity. Wrong mass = wrong peptide
- Endotoxin Testing (LAL Assay)
- Bacterial contamination from synthesis or handling
- ≤1 EU/mg endotoxin units
- >1 EU/mg, or endotoxin data absent from CoA
- Critical for in vivo research. Elevated endotoxins confound immune response data
- Third-Party CoA Verification
- Independent analytical lab confirmation
- CoA from accredited third-party lab (not in-house), includes batch number and test date
- In-house testing only, no lab name, generic CoA reused across batches
- Chain-of-custody proof. In-house CoAs can be fabricated without oversight