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Selank Amidate GABA Modulation: Dosing Protocol Comparison
Intranasal (most common) 600–900mcg daily (split 2–3 doses) 15–30 minutes 4–6 hours per dose α2/α3 upregulation begins day 3–5 Best for acute anxiety management. Fastest onset, shortest half-life, requires multiple daily doses Subcutaneous 300–600mcg daily (si
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- Intranasal (most common)
- 600–900mcg daily (split 2–3 doses)
- 15–30 minutes
- 4–6 hours per dose
- α2/α3 upregulation begins day 3–5
- Best for acute anxiety management. Fastest onset, shortest half-life, requires multiple daily doses
- Subcutaneous
- 300–600mcg daily (single dose)
- 30–60 minutes
- 6–8 hours
- Preferred for sustained protocols. Longer plasma half-life (90 min vs 25 min), fewer daily administrations
- Oral (not recommended)
- Not applicable
- Degraded by gastric peptidases
- Selank is a peptide. Oral administration results in complete proteolytic degradation before absorption