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Full sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 H-Lys-Pro-Val-OH Residue count 13 amino acids 3 amino acids Molecular weight 1664.9 g/mol 357.45 g/mol N-terminus Acetylated Free amine (lysine) C-terminus Amide (-NH2) Free acid (-OH) Me
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- Full sequence
- Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
- H-Lys-Pro-Val-OH
- Residue count
- 13 amino acids
- 3 amino acids
- Molecular weight
- 1664.9 g/mol
- 357.45 g/mol
- N-terminus
- Acetylated
- Free amine (lysine)
- C-terminus
- Amide (-NH2)
- Free acid (-OH)
- Melanocortin receptor binding
- Strong (MC1R, MC3R, MC4R, MC5R)
- Minimal to absent in most studies
- Primary anti-inflammatory mechanism
- MCR-mediated signaling
- Partly receptor-independent (intracellular)
- PepT1 substrate
- No (too large)
- Yes
- Oral stability
- Lower (larger, more protease-susceptible)
- Higher (small, proline-stabilized)
- Pigmentation effects
- Yes (MC1R in melanocytes)
- Absent or minimal
- Published research volume
- Extensive (50+ years)
- Moderate (20+ years, focused)
- CAS Number
- 581-05-5
- 69079-94-3