Understand the source comparison
Published Study Doses Versus Personal Medical Advice
A published mouse dose answers a narrow experimental question: what exposure researchers chose for a specific model, route, duration, and endpoint. It does not answer whether a compound is safe, effective, legal, or appropriate for a person. Human-equivalent d
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- A published mouse dose answers a narrow experimental question: what exposure researchers chose for a specific model, route, duration, and endpoint. It does not answer whether a compound is safe, effective, legal, or appropriate for a person.
- Human-equivalent dose calculations are also not enough. Drug development requires absorption, distribution, metabolism, excretion, toxicology, adverse-event monitoring, and dose-response data before a dose can be considered in clinical practice 14.