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Peptide Therapy GuideClear peptide education

Understand the source comparison

Peptides Intermittent Fasting Timing Guide: Comparison

GHRP-6 45–60 min pre-meal 14–18 hours 6–9 Insulin <10 μIU/mL Fat loss focus, appetite tolerance Hexarelin 30–45 min pre-meal 12–16 hours 8–12 Insulin <8 μIU/mL Maximum GH response, short-term use (desensitisation risk) Ipamorelin 40–60 min pre-meal 16–20 hours

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • GHRP-6
  • 45–60 min pre-meal
  • 14–18 hours
  • 6–9
  • Insulin <10 μIU/mL
  • Fat loss focus, appetite tolerance
  • Hexarelin
  • 30–45 min pre-meal
  • 12–16 hours
  • 8–12
  • Insulin <8 μIU/mL
  • Maximum GH response, short-term use (desensitisation risk)
  • Ipamorelin
  • 40–60 min pre-meal
  • 16–20 hours
  • 4–6
  • Extended fasts, minimal hunger stimulation
  • CJC-1295 (no DAC)
  • 5–8 (sustained 3–4 hrs)
  • Insulin <12 μIU/mL
  • Combining with GHRP for prolonged GH elevation
  • CJC-1295/Ipamorelin blend
  • 50–60 min pre-meal
  • 16–18 hours
  • 7–10 (sustained 4 hrs)
  • Peptides intermittent fasting protocols requiring both pulse amplitude and duration
  • MK-677 (oral)
  • Upon waking or 60 min pre-meal
  • 3–5 (chronic elevation)
  • Insulin <15 μIU/mL
  • Daily GH elevation without injections, less fasting-specific
  • The comparison shows that peptide selection depends on fasting duration, GH amplitude goals, and tolerance for appetite stimulation. Hexarelin produces the highest GH peaks but desensitises ghrelin receptors with daily use beyond 4–6 weeks. Ipamorelin offers the cleanest fasting compatibility because it doesn't trigger hunger. CJC-1295 combinations extend the GH window, which is valuable when breaking a fast with a protein-heavy meal that benefits from sustained amino acid uptake.