Understand the source comparison
Peptides for Telomere Lengthening: Full Comparison
Before selecting a research peptide, compare mechanism specificity, evidence quality, and biological risk profile across candidates. Thymalin Thymic regeneration → naive T-cell expansion with longer baseline telomeres Moderate (Russian clinical trials, small s
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Before selecting a research peptide, compare mechanism specificity, evidence quality, and biological risk profile across candidates.
- Thymalin
- Thymic regeneration → naive T-cell expansion with longer baseline telomeres
- Moderate (Russian clinical trials, small sample sizes)
- 10mg IM 3x/week for 4 weeks
- Immunosenescence
- Low (no telomerase activation)
- MK-677 (Ibutamoren)
- GH/IGF-1 ↑ → mitochondrial function ↑ → reduced oxidative telomere damage
- High (Phase II trials in sarcopenia, metabolic aging)
- 10–25mg oral daily
- Mitochondrial health, anabolic signaling
- Low (indirect pathway, no hTERT upregulation)
- Epithalon
- Claimed hTERT activation → direct telomerase upregulation
- Low (no independent replication, no Phase III data)
- 1mg SC daily for 10–20 days
- Direct telomerase modulation (unproven)
- Theoretical high (telomerase activation without tissue control)
- Cerebrolysin
- Neurotrophic support → reduced neuroinflammation → preserved neural progenitor telomere length
- Moderate (stroke recovery trials show secondary cognitive benefits)
- 10–30mL IV over 10–20 sessions
- Neuroinflammation, synaptic plasticity
- Low (brain-specific, no systemic telomerase effect)
- Dihexa
- HGF/c-Met pathway ↑ → neurogenesis ↑ (telomere correlation unclear)
- Low (rodent models only, no human trials)
- Research use: 1–5mg oral (experimental)
- Cognitive enhancement, neuroplasticity
- Unknown (insufficient long-term data)