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Peptides and Mediterranean Diet Synergy: Protocol Comparison
Fasted Morning Dosing Dose upon waking, eat 2+ hours later Standard Western breakfast (high glycemic, low polyphenol) Avoids food interference with absorption Baseline (no enhancement) Standard protocol. Misses receptor upregulation and polyphenol synergy enti
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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Fasted Morning Dosing
- Dose upon waking, eat 2+ hours later
- Standard Western breakfast (high glycemic, low polyphenol)
- Avoids food interference with absorption
- Baseline (no enhancement)
- Standard protocol. Misses receptor upregulation and polyphenol synergy entirely
- Pre-Lunch Mediterranean Timing
- Dose 60 min before lunch
- Olive oil-rich salad, legumes, whole grain, moderate protein
- GLP-1 receptor upregulation from PPAR-gamma activation
- +15–18% plasma concentration at 4hr
- Optimal for satiety extension and daytime appetite control
- Pre-Dinner Mediterranean Timing
- Dose 90 min before dinner
- Fatty fish, roasted vegetables in olive oil, quinoa or farro
- Polyphenol-mediated COMT inhibition + delayed gastric emptying
- +18–22% receptor density increase
- Best for evening appetite suppression and overnight metabolic rate
- Split-Dose Protocol
- Half-dose fasted AM, half-dose 60 min pre-dinner
- Mediterranean dinner only
- Combines baseline absorption with evening receptor window
- Moderate enhancement (+8–12%)
- Practical for patients who can't restructure lunch but want synergy benefits