Understand the source comparison
LL-37 CIRS Support: Protocol Comparison
Typical symptom improvement timeline 10–14 weeks 6–8 weeks 8–10 weeks Combined approaches show faster resolution. Gut repair addresses root permeability, binders clear circulating toxins TGF-beta1 reduction (% from baseline) 20–30% by week 8 35–50% by week 8 3
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- Typical symptom improvement timeline
- 10–14 weeks
- 6–8 weeks
- 8–10 weeks
- Combined approaches show faster resolution. Gut repair addresses root permeability, binders clear circulating toxins
- TGF-beta1 reduction (% from baseline)
- 20–30% by week 8
- 35–50% by week 8
- 30–40% by week 8
- Gut repair enhances LL-37 receptor sensitivity by reducing systemic LPS load
- MSH normalisation rate
- 40% of patients by week 12
- 65% of patients by week 10
- 55% of patients by week 10
- MSH recovery depends on hypothalamic inflammation clearing. Gut protocols accelerate this
- Relapse rate after stopping
- 50–60% within 6 months
- 30–40% within 6 months
- 35–45% within 6 months
- Addressing permeability and detox pathways creates more durable immune resilience
- Cost (12-week protocol)
- $480–720
- $720–960
- $600–840
- Gut repair adds supplement cost but reduces relapse-related expenses long-term