Understand the source comparison
Is FOXO4-DRI Safe? Side Effects Comparison
Hepatotoxicity (elevated liver enzymes) Yes. Transient ALT/AST elevation Mild to moderate 48–72 hours Low. But chronic use unstudied Gastrointestinal disturbance Yes. Diarrhoea, reduced appetite Mild 24–48 hours Moderate. Gut turnover in humans is slower than
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- Hepatotoxicity (elevated liver enzymes)
- Yes. Transient ALT/AST elevation
- Mild to moderate
- 48–72 hours
- Low. But chronic use unstudied
- Gastrointestinal disturbance
- Yes. Diarrhoea, reduced appetite
- Mild
- 24–48 hours
- Moderate. Gut turnover in humans is slower than rodents
- Immune suppression (WBC reduction)
- Yes. At doses ≥10 mg/kg
- Moderate
- 10–14 days
- Unknown. Dose-dependent, threshold unclear
- Cardiovascular effects
- Not reported
- N/A
- Unknown. No long-term monitoring conducted
- Reproductive harm
- Not studied
- Unknown. No multi-generational studies exist
- Neurotoxicity
- Unknown. Behavioural assays not included in protocols