Understand the source comparison
How to Run Tesofensine Cycle: Protocol Comparison
Conservative 0.25–0.5mg daily 14 days 21 days First-time users, subjects with cardiovascular concerns, or those sensitive to stimulants Lowest risk profile. Slower results but preserves long-term sensitivity and minimises rebound Standard 0.5–0.75mg daily 18 d
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Conservative
- 0.25–0.5mg daily
- 14 days
- 21 days
- First-time users, subjects with cardiovascular concerns, or those sensitive to stimulants
- Lowest risk profile. Slower results but preserves long-term sensitivity and minimises rebound
- Standard
- 0.5–0.75mg daily
- 18 days
- Experienced users with stable cardiovascular parameters and prior stimulant tolerance
- Balanced risk-to-benefit. The most commonly used protocol in research settings
- Aggressive
- 0.75–1mg daily
- Experienced users with high body weight (>90kg) and documented tolerance to monoaminergic compounds
- Higher efficacy but significantly increased cardiovascular load and rebound appetite risk
- Extended Low-Dose
- 0.25mg daily
- 28–42 days
- Long-term metabolic studies where appetite suppression is secondary to insulin sensitivity or lipid changes
- Not ideal for weight loss. Better suited for studying non-appetite mechanisms over extended timeframes