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Peptide Therapy GuideClear peptide education

Understand the source comparison

How much of GLP-1 weight loss is fat versus muscle?

Both are lost, but fat preferentially. Across incretin studies, lean mass accounts for roughly 20–40% of total weight lost, while fat makes up the majority, so the proportion of lean mass to total mass usually rises.68 This is why serious trials use DXA rather

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  • Both are lost, but fat preferentially. Across incretin studies, lean mass accounts for roughly 20–40% of total weight lost, while fat makes up the majority, so the proportion of lean mass to total mass usually rises.68 This is why serious trials use DXA rather than the scale, and why preserving muscle with resistance training and adequate protein is an active clinical focus.27 A photograph cannot distinguish fat loss from muscle or water loss at all.