Understand the source comparison
FOXO4-DRI Blood Work Labs: Standard vs Research-Grade Comparison
Baseline Timing Within 30 days of start Within 7 days of first dose Research-grade timing eliminates inflammatory variability; 30-day window allows too much baseline drift CBC Differential 5-part differential 5-part + absolute counts Absolute counts required t
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Baseline Timing
- Within 30 days of start
- Within 7 days of first dose
- Research-grade timing eliminates inflammatory variability; 30-day window allows too much baseline drift
- CBC Differential
- 5-part differential
- 5-part + absolute counts
- Absolute counts required to detect real immune shifts vs percentage artifacts
- Inflammatory Markers
- hs-CRP only
- hs-CRP + IL-6 + TNF-alpha
- IL-6 is more senescence-specific than CRP alone; TNF-alpha optional but valuable
- Follow-Up Schedule
- Week 8 only
- Weeks 4, 8, 12
- Single timepoint misses clearance dynamics and safety window
- Senescence Markers
- Not included
- p16INK4a, SA-beta-gal
- Direct markers prove mechanism but require specialized labs
- eGFR Threshold
- >30 mL/min acceptable
- >60 mL/min required
- Research protocols exclude Stage 3+ CKD due to unpredictable peptide clearance