Understand the source comparison
DSIP COA Elements: Testing Methods Comparison
HPLC Chromatography Purity by peak area integration ≥95% primary peak, baseline resolution Quantifies relative abundance of DSIP vs impurities Missing chromatogram image, baseline drift, split peaks, no detector wavelength listed Mass Spectrometry (ESI or MALD
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- HPLC Chromatography
- Purity by peak area integration
- ≥95% primary peak, baseline resolution
- Quantifies relative abundance of DSIP vs impurities
- Missing chromatogram image, baseline drift, split peaks, no detector wavelength listed
- Mass Spectrometry (ESI or MALDI)
- Molecular weight confirmation
- ±1 Da from 848.81 Da expected mass
- Confirms peptide identity. Prevents substitution or degradation
- Calculated mass only (no spectrum), mass deviation >1 Da, excessive fragmentation
- Lab Accreditation (ISO 17025)
- Quality system and method validation
- ISO/IEC 17025 from recognised body
- Ensures testing procedures meet international standards
- No accreditation listed, unknown lab, self-testing by vendor
- Batch Traceability
- Links COA to specific vial
- Batch number, test date, expiration date
- Prevents COA reuse across different batches
- Batch mismatch, test date >12 months old, no expiration date
- Endotoxin Testing (LAL assay)
- Bacterial contamination levels
- <10 EU/mg for research use
- Critical for in vivo studies. Endotoxins cause immune responses
- No endotoxin data, values >50 EU/mg, or test method not stated