Understand the source comparison
DSIP Administration: Protocol Comparison
Dose Range 0.5–1mg subcutaneous 1.5–2mg subcutaneous Higher doses show diminishing returns above 2mg. Receptor saturation occurs around 1.8mg in most protocols Injection Timing 45–60 minutes pre-sleep 30–45 minutes pre-sleep Timing precision matters more than
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Dose Range
- 0.5–1mg subcutaneous
- 1.5–2mg subcutaneous
- Higher doses show diminishing returns above 2mg. Receptor saturation occurs around 1.8mg in most protocols
- Injection Timing
- 45–60 minutes pre-sleep
- 30–45 minutes pre-sleep
- Timing precision matters more than dose. 30-minute variance reduces delta-wave extension by 18%
- Frequency
- 5–6 nights per week
- Nightly for 14–21 days
- Cycling appears unnecessary. DSIP does not downregulate delta-opioid receptors with continuous use
- Reconstitution Volume
- 1mg/mL (5mL per 5mg vial)
- 2mg/mL (2.5mL per 5mg vial)
- Higher concentration reduces injection volume but increases user error risk during measuring
- Storage Post-Reconstitution
- 2–8°C, use within 28 days
- 2–8°C, use within 21 days
- Bacterial growth begins day 28–30 in bacteriostatic water. Conservative 21-day limit eliminates risk