Understand the source comparison
DSIP 30s Age Specific Protocol: Comparison Table
20–29 50–75 mcg 30–45 min before Daily or 6 nights/week GABAergic tone, minimal HPA intervention needed Works well with sharp cortisol rhythms; lower dose sufficient 30–39 75–125 mcg 45–60 min before 5-on-2-off cycle HPA axis modulation, cortisol tail reductio
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- 20–29
- 50–75 mcg
- 30–45 min before
- Daily or 6 nights/week
- GABAergic tone, minimal HPA intervention needed
- Works well with sharp cortisol rhythms; lower dose sufficient
- 30–39
- 75–125 mcg
- 45–60 min before
- 5-on-2-off cycle
- HPA axis modulation, cortisol tail reduction
- Sweet spot for balancing efficacy and receptor preservation
- 40–49
- 100–150 mcg
- 60–75 min before
- 4-on-3-off or intermittent
- Slow-wave restoration, cortisol flattening mitigation
- Higher dose compensates for deeper HPA dysregulation
- 50+
- 125–250 mcg
- 75–90 min before
- Intermittent (3–4×/week)
- Mitochondrial support, severe cortisol rhythm correction
- Risk of tolerance; cycling essential to maintain response