Understand the source comparison
Does SS-31 Need Refrigeration Storage?: Peptide Comparison
SS-31 (Elamipretide) −20°C long-term; tolerates 20–25°C for 2–3 weeks 2–8°C, use within 28 days High. Aromatic residues oxidise above 8°C Dimethyltyrosine oxidation, hydrolytic cleavage Requires strict refrigeration post-mix; brief room temp excursions accepta
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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- SS-31 (Elamipretide)
- −20°C long-term; tolerates 20–25°C for 2–3 weeks
- 2–8°C, use within 28 days
- High. Aromatic residues oxidise above 8°C
- Dimethyltyrosine oxidation, hydrolytic cleavage
- Requires strict refrigeration post-mix; brief room temp excursions acceptable pre-reconstitution only
- BPC-157
- −20°C preferred; stable at room temp 1–2 weeks
- 2–8°C, use within 30 days
- Moderate. Stable pentadecapeptide
- Hydrolysis at Gly-Pro bonds
- More forgiving than SS-31; tolerates occasional temp spikes better due to lack of oxidisable aromatics
- Thymosin Beta-4 (TB-500)
- −20°C long-term; 2–8°C short-term
- Moderate. Acetylated N-terminus adds stability
- Hydrolysis, aggregation at high concentration
- Similar refrigeration requirement; aggregation risk higher than SS-31 at >1 mg/mL
- Cerebrolysin
- 2–8°C only (pre-filled ampules)
- N/A (single-use format)
- Low. Neuropeptide mixture in stable formulation
- Minimal if stored correctly
- Manufacturer-stabilised; does not require freezing but must stay refrigerated