Understand the source comparison
Do Peptides Help With Increasing Growth Hormone Naturally: Key Comparisons
GHRP-2 Ghrelin receptor agonist 7–10× baseline 30–50% Low to moderate (cycle after 8–12 weeks) 100mcg 2–3×/day subcutaneous GHRP-6 6–9× baseline 25–45% Moderate (notable appetite increase) Hexarelin 10–12× baseline 40–60% High (receptor downregulation after 4–
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- GHRP-2
- Ghrelin receptor agonist
- 7–10× baseline
- 30–50%
- Low to moderate (cycle after 8–12 weeks)
- 100mcg 2–3×/day subcutaneous
- GHRP-6
- 6–9× baseline
- 25–45%
- Moderate (notable appetite increase)
- Hexarelin
- 10–12× baseline
- 40–60%
- High (receptor downregulation after 4–6 weeks)
- 100mcg 1–2×/day, cycled
- Ipamorelin
- Selective GHS-R1a agonist
- 3–5× baseline
- 20–35%
- Very low (minimal cortisol/prolactin effect)
- 200–300mcg 2–3×/day subcutaneous
- Modified GRF(1-29)
- GHRH receptor agonist
- Amplifies natural pulse 3–5×
- 15–30% (synergistic with GHRPs)
- Very low
- 100mcg 2–3×/day with GHRP
- CJC-1295 (DAC)
- Extended GHRH agonist
- Sustained mild elevation
- Low
- 30mcg/kg weekly subcutaneous
- MK-677 (ibutamoren)
- Oral ghrelin mimetic
- 2–4× baseline (sustained)
- 40–90%
- Low (chronic elevation, not pulsatile)
- 25mg once daily oral