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Peptide Therapy GuideClear peptide education

Understand the source comparison

Do Peptides Help With Increasing Growth Hormone Naturally: Key Comparisons

GHRP-2 Ghrelin receptor agonist 7–10× baseline 30–50% Low to moderate (cycle after 8–12 weeks) 100mcg 2–3×/day subcutaneous GHRP-6 6–9× baseline 25–45% Moderate (notable appetite increase) Hexarelin 10–12× baseline 40–60% High (receptor downregulation after 4–

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • GHRP-2
  • Ghrelin receptor agonist
  • 7–10× baseline
  • 30–50%
  • Low to moderate (cycle after 8–12 weeks)
  • 100mcg 2–3×/day subcutaneous
  • GHRP-6
  • 6–9× baseline
  • 25–45%
  • Moderate (notable appetite increase)
  • Hexarelin
  • 10–12× baseline
  • 40–60%
  • High (receptor downregulation after 4–6 weeks)
  • 100mcg 1–2×/day, cycled
  • Ipamorelin
  • Selective GHS-R1a agonist
  • 3–5× baseline
  • 20–35%
  • Very low (minimal cortisol/prolactin effect)
  • 200–300mcg 2–3×/day subcutaneous
  • Modified GRF(1-29)
  • GHRH receptor agonist
  • Amplifies natural pulse 3–5×
  • 15–30% (synergistic with GHRPs)
  • Very low
  • 100mcg 2–3×/day with GHRP
  • CJC-1295 (DAC)
  • Extended GHRH agonist
  • Sustained mild elevation
  • Low
  • 30mcg/kg weekly subcutaneous
  • MK-677 (ibutamoren)
  • Oral ghrelin mimetic
  • 2–4× baseline (sustained)
  • 40–90%
  • Low (chronic elevation, not pulsatile)
  • 25mg once daily oral