Understand the source comparison
Do Peptides Help with Endurance: Comparison
MK 677 Growth hormone secretagogue; increases IGF-1 and mitochondrial biogenesis VO2 max, lactate threshold, glycogen storage rate 10-25mg daily, oral Best-supported peptide for endurance; effects are training-dependent and require 8-12 weeks to manifest Cereb
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- MK 677
- Growth hormone secretagogue; increases IGF-1 and mitochondrial biogenesis
- VO2 max, lactate threshold, glycogen storage rate
- 10-25mg daily, oral
- Best-supported peptide for endurance; effects are training-dependent and require 8-12 weeks to manifest
- Cerebrolysin
- Neurotrophic peptide blend; reduces neuroinflammation, improves motor unit recruitment
- Recovery time, CNS fatigue resistance, interval repeatability
- 5-10mL IV or IM, 2-3x weekly
- Indirect endurance benefit through recovery and neuromuscular efficiency; expensive and requires injection protocol
- Thymalin
- Thymic peptide; upregulates endogenous EPO, immune modulation
- Hemoglobin concentration, oxygen-carrying capacity
- 10mg subcutaneous, daily for 10-20 days
- Promising but under-researched in Western literature; most data from Russian sports medicine; legal and safety profile well-established
- CJC-1295/Ipamorelin blend
- Growth hormone releasing peptides; pulsatile GH elevation
- Mitochondrial function, tissue repair, sleep quality (indirect endurance benefit)
- 100-200mcg each peptide, nightly subcutaneous
- Comparable to MK 677 but requires injection; some athletes prefer pulsatile GH over continuous elevation for training adaptation
- Exogenous EPO (not recommended)
- Direct erythropoiesis stimulation
- VO2 max, hemoglobin, oxygen delivery
- N/A. Banned substance
- Most potent endurance peptide but carries serious health risks (stroke, MI, polycythemia); included for mechanism comparison only