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Peptide Therapy GuideClear peptide education

Understand the source comparison

Do Peptides Help with Endurance: Comparison

MK 677 Growth hormone secretagogue; increases IGF-1 and mitochondrial biogenesis VO2 max, lactate threshold, glycogen storage rate 10-25mg daily, oral Best-supported peptide for endurance; effects are training-dependent and require 8-12 weeks to manifest Cereb

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • MK 677
  • Growth hormone secretagogue; increases IGF-1 and mitochondrial biogenesis
  • VO2 max, lactate threshold, glycogen storage rate
  • 10-25mg daily, oral
  • Best-supported peptide for endurance; effects are training-dependent and require 8-12 weeks to manifest
  • Cerebrolysin
  • Neurotrophic peptide blend; reduces neuroinflammation, improves motor unit recruitment
  • Recovery time, CNS fatigue resistance, interval repeatability
  • 5-10mL IV or IM, 2-3x weekly
  • Indirect endurance benefit through recovery and neuromuscular efficiency; expensive and requires injection protocol
  • Thymalin
  • Thymic peptide; upregulates endogenous EPO, immune modulation
  • Hemoglobin concentration, oxygen-carrying capacity
  • 10mg subcutaneous, daily for 10-20 days
  • Promising but under-researched in Western literature; most data from Russian sports medicine; legal and safety profile well-established
  • CJC-1295/Ipamorelin blend
  • Growth hormone releasing peptides; pulsatile GH elevation
  • Mitochondrial function, tissue repair, sleep quality (indirect endurance benefit)
  • 100-200mcg each peptide, nightly subcutaneous
  • Comparable to MK 677 but requires injection; some athletes prefer pulsatile GH over continuous elevation for training adaptation
  • Exogenous EPO (not recommended)
  • Direct erythropoiesis stimulation
  • VO2 max, hemoglobin, oxygen delivery
  • N/A. Banned substance
  • Most potent endurance peptide but carries serious health risks (stroke, MI, polycythemia); included for mechanism comparison only