Understand the source comparison
Do Peptides Help With Body Recomposition: Comparison
CJC-1295/Ipamorelin GHRH analog + ghrelin mimetic. Synergistic GH release without cortisol elevation +1.2–2.6 kg over 12–24 weeks (DEXA-measured) Visceral fat reduction 8–12% in deficit or maintenance intake Subcutaneous injection, requires reconstitution and
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- CJC-1295/Ipamorelin
- GHRH analog + ghrelin mimetic. Synergistic GH release without cortisol elevation
- +1.2–2.6 kg over 12–24 weeks (DEXA-measured)
- Visceral fat reduction 8–12% in deficit or maintenance intake
- Subcutaneous injection, requires reconstitution and refrigeration
- Gold standard for recomposition. Strongest evidence, minimal side effects, no desensitization
- MK-677
- Oral ghrelin receptor agonist. Sustained 24-hour GH/IGF-1 elevation
- +1.1 kg lean mass over 8 weeks
- 9.3% visceral fat reduction (Growth Hormone & IGF Research, 2019)
- Oral capsule, no reconstitution needed
- Effective but higher appetite and transient insulin resistance risk. Monitor fasting glucose
- Hexarelin
- GHSR-1a agonist. Potent GH pulse, receptor desensitization after 4–6 weeks
- +0.9–1.4 kg lean mass (short-term studies)
- Moderate lipolytic effect, less studied than CJC/Ipa
- Subcutaneous injection, pulsed protocol required
- Strong short-term effect but desensitization limits long-term use. Best for 4-week cycles
- BPC-157
- Tissue repair peptide. No direct GH/IGF-1 modulation
- No evidence for lean mass gain
- No evidence for fat loss
- Subcutaneous or oral
- No recomposition mechanism. Supports recovery, not body composition change
- Collagen Peptides
- Structural protein. Supports connective tissue synthesis
- No muscle protein synthesis benefit
- No lipolytic effect
- Oral powder
- Not a body recomposition tool. Supports joint and skin health only