Understand the source comparison
Comparison table
Feature P21 Cerebrolysin Semax Selank Adamax Origin Synthetic CNTF mimetic Porcine brain-derived Synthetic ACTH analogue Synthetic tuftsin analogue Synthetic adamantane peptide Primary mechanism LIF inhibition, BDNF upregulation Broad neurotrophic support Sero
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Feature
- P21
- Cerebrolysin
- Semax
- Selank
- Adamax
- Origin
- Synthetic CNTF mimetic
- Porcine brain-derived
- Synthetic ACTH analogue
- Synthetic tuftsin analogue
- Synthetic adamantane peptide
- Primary mechanism
- LIF inhibition, BDNF upregulation
- Broad neurotrophic support
- Serotonin/dopamine modulation
- Anxiolytic, immunomodulation
- TrkB sensitization, BDNF
- Neurogenesis
- Strong
- Moderate
- Mild
- Tau protection
- Some evidence
- Limited data
- Not studied
- Administration
- Intranasal, SubQ, Oral
- IM/IV injection
- Intranasal
- Intranasal, SubQ
- Human clinical data
- None
- Extensive
- Approved in Russia
- Immunogenicity risk
- Very low
- Moderate (anti-CNTF antibodies)
- Low
- Best for
- Neurogenesis, neuroprotection
- Broad neural recovery
- Focus, memory, mood
- Anxiety, calm focus
- BDNF/TrkB optimization