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Peptide Therapy GuideClear peptide education

Understand the source comparison

Comparison: Hexarelin Fat Loss Results Timeline vs Other GH Secretagogues

Hexarelin GHS-R1a agonist (selective) 4–6 weeks (VAT), 10–12 weeks (SAT) 6–10× baseline Minimal at doses ≤400mcg/day Fastest visceral fat mobilization among GH secretagogues, minimal ghrelin-driven appetite increase makes it ideal for fat loss protocols Ipamor

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • Hexarelin
  • GHS-R1a agonist (selective)
  • 4–6 weeks (VAT), 10–12 weeks (SAT)
  • 6–10× baseline
  • Minimal at doses ≤400mcg/day
  • Fastest visceral fat mobilization among GH secretagogues, minimal ghrelin-driven appetite increase makes it ideal for fat loss protocols
  • Ipamorelin
  • GHS-R1a agonist (highly selective)
  • 6–8 weeks (VAT), 12–14 weeks (SAT)
  • 3–5× baseline
  • Slowest timeline but cleanest side effect profile. No cortisol or prolactin elevation, suitable for longer protocols
  • GHRP-6
  • Ghrelin receptor agonist (non-selective)
  • 8–10 weeks (combined VAT/SAT)
  • 8–12× baseline
  • Significant (hunger spikes 30–60 min post-dose)
  • Strong GH response but appetite stimulation counteracts fat loss. Requires strict dietary control
  • MK 677 (Ibutamoren)
  • Oral GHS-R1a agonist
  • 10–14 weeks (combined VAT/SAT)
  • 4–6× baseline sustained 24h
  • Moderate to significant
  • Oral convenience with sustained GH elevation, but water retention and appetite increase complicate fat loss interpretation
  • CJC-1295 + Ipamorelin
  • GHRH analog + GHS-R1a agonist (combination)
  • 6–10 weeks (VAT), 12–16 weeks (SAT)
  • 5–8× baseline (synergistic)
  • Synergistic GH pulse amplitude and frequency increase. Effective but requires twice-daily dosing for optimal results