Understand the source comparison
Comparison at a glance
DSIP (Delta Sleep-Inducing Peptide) Named for promoting slow-wave (delta) sleep; the only one of the three tested directly for sleep in humans Preclinical + small, dated human studies — mixed to negative Best-controlled human trial found the effect weak and of
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- DSIP (Delta Sleep-Inducing Peptide)
- Named for promoting slow-wave (delta) sleep; the only one of the three tested directly for sleep in humans
- Preclinical + small, dated human studies — mixed to negative
- Best-controlled human trial found the effect weak and of little therapeutic value
- Epithalon (Epitalon / AEDG)
- Studied as a pineal peptide that may modulate melatonin and circadian rhythm
- Preclinical + limited human melatonin-marker data; no sleep-outcome trials
- Link to sleep is indirect (via melatonin) and comes mostly from one research group
- Pinealon (EDR / Glu-Asp-Arg)
- Studied for neuroprotection, antioxidant activity, and cognition — not sleep
- Preclinical only; no identified sleep studies
- Its “sleep peptide” label rests on the pineal name, not on sleep data