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Comparison: Adamax Dosing Protocols for Different Research Goals
Baseline cognitive support & neuroprotection 5mg once daily Morning (within 60 min of waking) 12+ weeks Sustained hippocampal BDNF upregulation; neuroprotective via MC4R/MC5R activation Optimal for long-term research models; well-tolerated with minimal side ef
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- Baseline cognitive support & neuroprotection
- 5mg once daily
- Morning (within 60 min of waking)
- 12+ weeks
- Sustained hippocampal BDNF upregulation; neuroprotective via MC4R/MC5R activation
- Optimal for long-term research models; well-tolerated with minimal side effects; most cost-effective protocol
- Acute cognitive task performance
- 7.5–10mg single dose
- 30–45 min before task
- Single administration
- Peak BDNF and glutamate receptor modulation during task window
- Best for time-limited cognitive demands; not suitable for chronic use at this dose
- Memory consolidation research
- Evening (60–90 min before sleep)
- 8–12 weeks
- Enhances sleep-dependent memory consolidation via hippocampal replay
- Emerging research; aligns BDNF peak with slow-wave sleep when memory consolidation occurs
- Executive function & working memory
- 10mg once daily
- Morning
- 8–16 weeks
- Prefrontal MC4R activation; sustained AMPA receptor upregulation
- Higher dose justified by prefrontal receptor distribution; monitor for overstimulation
- Cognitive aging & neurodegeneration models
- 24+ weeks
- Long-term neuroprotection; mitigation of age-related BDNF decline
- Supported by long-term Russian clinical data; safety profile well-established at this dose