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Comparative Analysis: Sermorelin versus Recombinant Human Growth Hormone

The choice between GHRH-based secretagogue therapy (sermorelin) and direct GH replacement (recombinant human growth hormone) represents a fundamental therapeutic decision with distinct mechanistic, pharmacological, and clinical implications. Systematic compari

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  • The choice between GHRH-based secretagogue therapy (sermorelin) and direct GH replacement (recombinant human growth hormone) represents a fundamental therapeutic decision with distinct mechanistic, pharmacological, and clinical implications. Systematic comparison of these approaches informs evidence-based treatment selection for patients with growth hormone insufficiency.