Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Understand the source comparison

Biossance Squalane + Retinol Night Serum Versus Medik8 Crystal Retinal

Biossance Squalane + Retinol Night Serum Versus Medik8 Crystal Retinal Detailed comparison of Biossance Squalane + Retinol Night Serum versus Medik8 Crystal Retinal 3. This anti-aging serum is formulated around Retinol and Retinal to soften the look of wrinkle

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

Biossance Squalane + Retinol Night Serum Versus Medik8 Crystal Retinal Detailed comparison of Biossance Squalane + Retinol Night Serum versus Medik8 Crystal Retinal 3. This anti-aging serum is formulated around Retinol and Retinal to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around 3-O-Ethyl Ascorbic Acid and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Squalane Glycerin Caprylic/Capric Triglyceride Cetearyl Olivate Sorbitan Olivate Retinol Retinal Allantoin Crocus Sativus Stigma Extract Pseudozyma Epicola/Evening Primrose Oil Ferment Extract Tocopherol Rosmarinus Officinalis Leaf Extract Oryza Sativa Bran Extract Cetearyl Alcohol Helianthus Annuus Extract Hydroxyapatite Dextrin Carbomer Sodium Gluconate Phenoxyethanol Ethylhexylglycerin Sodium Hydroxide Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Olivate, Sorbitan Olivate, Retinol, Retinal, Allantoin, Crocus Sativus Stigma Extract, Pseudozyma Epicola/Evening Primrose Oil Ferment Extract, Tocopherol, Rosmarinus Officinalis Leaf Extract, Oryza Sativa Bran Extract, Cetearyl Alcohol, Helianthus Annuus Extract, Hydroxyapatite, Dextrin, Carbomer, Sodium Gluconate, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide Isododecane Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer PPG-12/Smdi Copolymer Tocopheryl Acetate Cyclodextrin Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Hydroxyacetophenone 3-O-Ethyl Ascorbic Acid Hydroxypropyl Methylcellulose Sodium Hyaluronate Tetrahexyldecyl Ascorbate Daucus Carota Sativa Seed Oil Rubus Chamaemorus Seed Oil Alumina Isostearic Acid Lecithin Polyglyceryl-3 Polyricinoleate Lonicera Japonica Flower Extract Lonicera Caprifolium Flower Extract Polyhydroxystearic Acid Stearic Acid Sodium Polyaspartate Pentylene Glycol Citric Acid Polysorbate 60 Disodium EDTA BHT Sorbitan Isostearate Vanilla Planifolia Fruit Extract Dipteryx Odorata Bean Extract Coumarin CI 14700 CI 77891 Water, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, 3-O-Ethyl Ascorbic Acid, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Phenoxyethanol, Tetrahexyldecyl Ascorbate, Daucus Carota Sativa Seed Oil, Retinal, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Polyhydroxystearic Acid, Stearic Acid, Sodium Polyaspartate, Pentylene Glycol, Citric Acid, Polysorbate 60, Disodium EDTA, Ethylhexylglycerin, BHT, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Dipteryx Odorata Bean Extract, Coumarin, CI 14700, CI 77891 Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier. Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient. It plays several roles in a formula: Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products. Multiple assessments have found it to be non-irritating and non-sensitizing to most people. However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers. Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy. Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans. Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients. This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize. A 2019 study has also observed Malassezia growth in the presence of this in