Understand the source comparison
Best Research Peptides for Osteoarthritis: Type Comparison
BPC-157 VEGF upregulation, collagen synthesis enhancement, inflammatory cytokine suppression 10 mcg/kg daily (subcutaneous) in animal models 28 days at 2–8°C 4–12 weeks Most studied for tendon-bone healing; angiogenic effects translate well to cartilage repair
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- BPC-157
- VEGF upregulation, collagen synthesis enhancement, inflammatory cytokine suppression
- 10 mcg/kg daily (subcutaneous) in animal models
- 28 days at 2–8°C
- 4–12 weeks
- Most studied for tendon-bone healing; angiogenic effects translate well to cartilage repair models
- TB-500
- Actin sequestration, cell migration promotion, synovial regeneration
- 5–10 mg per dose, twice weekly
- 4–8 weeks
- Longer tissue half-life than BPC-157; stronger evidence for soft tissue regeneration than cartilage-specific repair
- GHK-Cu
- MMP inhibition (MMP-1, -2, -9), TIMP expression increase, copper-dependent collagen stabilization
- 2–5 mg/kg (intra-articular or subcutaneous)
- 21 days at 2–8°C (copper oxidation limits window)
- 6–12 weeks
- Direct anti-degradation mechanism; most relevant for slowing cartilage breakdown in established OA models