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Best Peptides for Wound Healing: Mechanism Comparison
The table below compares mechanism, dosage range from published studies, and primary phase of action for the most-studied peptides in wound healing research. BPC-157 VEGF upregulation, angiogenesis, fibroblast proliferation 10–20 mcg/kg subcutaneous Proliferat
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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- The table below compares mechanism, dosage range from published studies, and primary phase of action for the most-studied peptides in wound healing research.
- BPC-157
- VEGF upregulation, angiogenesis, fibroblast proliferation
- 10–20 mcg/kg subcutaneous
- Proliferation (days 3–14)
- Animal models, limited human data
- Strongest preclinical evidence for ischemic and tendon injuries
- TB-500
- Actin regulation, cell migration, anti-apoptotic signaling
- 2–10 mg weekly systemic
- Proliferation and migration (days 2–10)
- Animal models, equine trials
- Effective in large-surface wounds requiring rapid re-epithelialization
- GHK-Cu
- Copper delivery, collagen cross-linking, matrix remodeling
- 0.05–0.1% topical or 2–5 mg injectable
- Remodeling (days 14–60+)
- Multiple human RCTs in chronic wounds
- FDA-cleared topical formulations exist; robust clinical support
- LL-37
- Antimicrobial, immune modulation, biofilm disruption
- 10–50 mcg/mL topical
- Inflammatory (days 1–5)
- In vitro and ex vivo models
- Critical for infected or biofilm-positive wounds before regenerative peptides