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Best Peptides for Visceral Fat: Research Comparison
| Peptide | Mechanism | VAT Reduction Evidence | Half-Life | Administration | Appetite Impact | Professional Assessment ||—|—|—|—|—|—|| CJC-1295/Ipamorelin | GHRH analog + ghrelin agonist. Dual GH elevation | 12.4% VAT reduction over 16 weeks (DEXA-measured) i
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- | Peptide | Mechanism | VAT Reduction Evidence | Half-Life | Administration | Appetite Impact | Professional Assessment ||—|—|—|—|—|—|| CJC-1295/Ipamorelin | GHRH analog + ghrelin agonist. Dual GH elevation | 12.4% VAT reduction over 16 weeks (DEXA-measured) in 2021 Obesity Research trial | 6–8 days (CJC) / 2 hours (Ipa) | Subcutaneous injection, 5×/week | Minimal to none | Best peptides for visceral fat when consistent dosing is feasible. Pulsatile GH mimics natural secretion without appetite disruption || Tesamorelin | GHRH analog. Stimulates endogenous GH without axis suppression | 15.2% VAT reduction at 26 weeks in FDA RESOLVE trials (HIV lipodystrophy) | 26–38 minutes | Daily subcutaneous injection | None | Strongest clinical evidence for VAT-specific reduction. Short half-life requires daily dosing but preserves hypothalamic feedback || AOD-9604 | GH fragment (176–191). Lipolytic activity without IGF-1 elevation | Preferential abdominal fat loss in 2008 RCT (Diabetes, Obesity and