Understand the source comparison
Best Peptides for Runners Knee: Protocol Comparison
BPC-157 VEGF upregulation, collagen synthesis 250–500 mcg/day Daily (subcutaneous, injury-proximal) 7–10 days for inflammation reduction Best for localized tendon repair. Direct angiogenic effect TB-500 Actin regulation, fibroblast migration 2–5 mg loading / 2
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- BPC-157
- VEGF upregulation, collagen synthesis
- 250–500 mcg/day
- Daily (subcutaneous, injury-proximal)
- 7–10 days for inflammation reduction
- Best for localized tendon repair. Direct angiogenic effect
- TB-500
- Actin regulation, fibroblast migration
- 2–5 mg loading / 2 mg maintenance
- Twice weekly loading / weekly maintenance
- 10–14 days for mobility improvement
- Best for systemic inflammation modulation and cell migration
- GHK-Cu
- Copper-dependent collagen crosslinking
- 1–3 mg/day
- Daily (subcutaneous, any site)
- 14–21 days for matrix remodeling
- Best for long-term tendon integrity. Strengthens repaired tissue
- The combination protocol we've observed delivering the most consistent outcomes pairs BPC-157 (250 mcg daily) with TB-500 (5 mg twice weekly for 4 weeks, then 2 mg weekly) during the acute recovery phase, adding GHK-Cu (2 mg daily) after week 3 to support collagen maturation during the remodeling phase. This sequencing matches the biological timeline of tendon repair: inflammation and angiogenesis first (BPC-157 + TB-500), followed by matrix organization and crosslinking (GHK-Cu).