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Best Peptides for Post ACL Surgery: Treatment Window Comparison
BPC-157 Upregulates VEGF and FAK-paxillin pathway; enhances fibroblast migration and collagen synthesis Inflammatory + Proliferative (weeks 0–6) 250–500 mcg/day subcutaneous 4–8 weeks Most evidence-supported for tendon-to-bone integration; start within 48 hour
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- BPC-157
- Upregulates VEGF and FAK-paxillin pathway; enhances fibroblast migration and collagen synthesis
- Inflammatory + Proliferative (weeks 0–6)
- 250–500 mcg/day subcutaneous
- 4–8 weeks
- Most evidence-supported for tendon-to-bone integration; start within 48 hours post-op
- TB-500
- Binds actin to promote organized collagen deposition; reduces inflammatory cytokines
- Inflammatory (weeks 0–2)
- 2–2.5 mg twice weekly subcutaneous
- 4–6 weeks
- Best for controlling early inflammation and preventing excessive scar tissue formation
- IGF-1 LR3
- Stimulates satellite cell proliferation; maintains anabolic signaling
- Proliferative + Remodeling (weeks 2–12)
- 40–80 mcg/day subcutaneous
- 6–10 weeks
- Critical for preserving muscle mass during immobilization; less direct graft impact