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Peptide Therapy GuideClear peptide education

Understand the source comparison

Best Peptides for Love Handles: Mechanism Comparison

CJC-1295/Ipamorelin GHRH analog + ghrelin mimetic. Sustained GH elevation without cortisol spike 6–8 days (CJC) / 2 hours (Ipamorelin) 2mg weekly CJC + 200–300mcg nightly Ipamorelin Systemic fat loss, slight visceral preference due to higher HSL receptor densi

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • CJC-1295/Ipamorelin
  • GHRH analog + ghrelin mimetic. Sustained GH elevation without cortisol spike
  • 6–8 days (CJC) / 2 hours (Ipamorelin)
  • 2mg weekly CJC + 200–300mcg nightly Ipamorelin
  • Systemic fat loss, slight visceral preference due to higher HSL receptor density
  • Most versatile stack for fat loss research. Minimal side effects, strong lipolytic signaling, long half-life reduces injection frequency
  • Tesamorelin
  • GHRH analog. FDA-approved for lipodystrophy, targets visceral adipose tissue
  • 26 minutes
  • 2mg daily subcutaneous
  • Strong visceral preference (15% reduction in trials), minimal subcutaneous effect
  • Best for visceral fat reduction, limited impact on love handles specifically. Requires daily dosing and higher cost
  • AOD-9604
  • C-terminal GH fragment. Lipolytic without IGF-1 elevation
  • 2 hours
  • 500mcg twice daily
  • Systemic, no preferential targeting
  • Safest option with lowest potency. 2–3% body fat reduction typical, no metabolic side effects, ideal for cautious first-time researchers
  • MK-677 (Ibutamoren)
  • Ghrelin receptor agonist. Oral GH secretagogue
  • 24 hours
  • 10–25mg daily oral
  • Systemic with moderate water retention
  • Convenient oral dosing but higher appetite stimulation and water retention. Less fat-specific than injectable peptides