Understand the source comparison
Best Peptides for Love Handles: Mechanism Comparison
CJC-1295/Ipamorelin GHRH analog + ghrelin mimetic. Sustained GH elevation without cortisol spike 6–8 days (CJC) / 2 hours (Ipamorelin) 2mg weekly CJC + 200–300mcg nightly Ipamorelin Systemic fat loss, slight visceral preference due to higher HSL receptor densi
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- CJC-1295/Ipamorelin
- GHRH analog + ghrelin mimetic. Sustained GH elevation without cortisol spike
- 6–8 days (CJC) / 2 hours (Ipamorelin)
- 2mg weekly CJC + 200–300mcg nightly Ipamorelin
- Systemic fat loss, slight visceral preference due to higher HSL receptor density
- Most versatile stack for fat loss research. Minimal side effects, strong lipolytic signaling, long half-life reduces injection frequency
- Tesamorelin
- GHRH analog. FDA-approved for lipodystrophy, targets visceral adipose tissue
- 26 minutes
- 2mg daily subcutaneous
- Strong visceral preference (15% reduction in trials), minimal subcutaneous effect
- Best for visceral fat reduction, limited impact on love handles specifically. Requires daily dosing and higher cost
- AOD-9604
- C-terminal GH fragment. Lipolytic without IGF-1 elevation
- 2 hours
- 500mcg twice daily
- Systemic, no preferential targeting
- Safest option with lowest potency. 2–3% body fat reduction typical, no metabolic side effects, ideal for cautious first-time researchers
- MK-677 (Ibutamoren)
- Ghrelin receptor agonist. Oral GH secretagogue
- 24 hours
- 10–25mg daily oral
- Systemic with moderate water retention
- Convenient oral dosing but higher appetite stimulation and water retention. Less fat-specific than injectable peptides