Understand the source comparison
Best Peptides for Jet Lag: Mechanism Comparison
Thymalin Restores T-cell differentiation blocked by cortisol mistiming Immune (thymus) 10 mg SC daily × 5–10 days 2–3 hours Addresses immune suppression. Not cognitive symptoms Cerebrolysin Delivers BDNF and NGF to enhance hippocampal synaptic plasticity Neuro
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- Thymalin
- Restores T-cell differentiation blocked by cortisol mistiming
- Immune (thymus)
- 10 mg SC daily × 5–10 days
- 2–3 hours
- Addresses immune suppression. Not cognitive symptoms
- Cerebrolysin
- Delivers BDNF and NGF to enhance hippocampal synaptic plasticity
- Neuroplasticity
- 10–30 mL IV (impractical for travel)
- 2–4 hours
- Most studied for circadian adaptation but requires IV
- Dihexa
- Enhances HGF signaling to support dendritic spine formation
- 1–5 mg SC daily
- 1–2 hours
- Practical SC alternative to Cerebrolysin
- Cartalax
- Upregulates PGC-1alpha to increase mitochondrial biogenesis
- Mitochondrial recovery
- 5–10 mg SC daily × 10–20 days
- <2 hours
- Compensates for ATP depletion in neurons
- P21
- Promotes neuronal survival under metabolic stress via CNTF pathway
- Neuroprotection
- 5–10 mg SC
- 1–3 hours
- Protects against stress but doesn't accelerate adaptation