Understand the source comparison
Best Peptides for Biological Age Reduction: Treatment Comparison
Epitalon Telomerase activation, pineal regulation Telomere length, circadian rhythm 10mg daily subcutaneous × 10–20 days, cycled every 4–6 months Strong. Human trials show 33% telomere extension Best evidence for direct telomere impact; requires cycling GHK-Cu
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Epitalon
- Telomerase activation, pineal regulation
- Telomere length, circadian rhythm
- 10mg daily subcutaneous × 10–20 days, cycled every 4–6 months
- Strong. Human trials show 33% telomere extension
- Best evidence for direct telomere impact; requires cycling
- GHK-Cu
- Gene expression modulation, copper delivery
- Collagen synthesis, DNA repair gene activity
- 1–3mg daily subcutaneous or topical for systemic effect
- Strong. Broad Institute gene analysis validates mechanism
- Impacts 70% of age-related gene expression changes
- Thymosin Beta-4
- Thymic regeneration, immune restoration
- Naïve T-cell count, thymic weight
- 5–10mg twice weekly subcutaneous, 8 weeks on/4 weeks off
- Moderate. Animal data strong, human immune data limited
- Addresses immune senescence directly; proven thymic effect
- MOTS-c
- Mitochondrial biogenesis, AMPK activation
- Insulin sensitivity, mitochondrial function
- 5–15mg 2–3× weekly intramuscular
- Moderate. Lifespan extension in mice, human metabolic data emerging
- Mimics caloric restriction metabolically without dietary change
- Humanin
- Neuroprotection, amyloid clearance
- Neuronal survival, cognitive function markers
- 2–5mg daily subcutaneous
- Moderate. Neuroprotection proven, longevity data in model organisms
- Strongest for brain aging; less systemic impact