Understand the source comparison
Best Peptides for Biohackers: Mechanism Comparison
BPC-157 VEGF upregulation, angiogenesis Tendon/ligament repair, gut healing 200–500 mcg/day split doses Subcutaneous injection Gold standard for injury recovery. Most validated peptide for soft tissue repair MK-677 Ghrelin receptor agonist → pulsatile GH relea
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- BPC-157
- VEGF upregulation, angiogenesis
- Tendon/ligament repair, gut healing
- 200–500 mcg/day split doses
- Subcutaneous injection
- Gold standard for injury recovery. Most validated peptide for soft tissue repair
- MK-677
- Ghrelin receptor agonist → pulsatile GH release
- Lean mass retention, sleep quality
- 25mg daily (evening)
- Oral capsule
- Reliable IGF-1 elevation without exogenous GH; manages appetite or it backfires
- MOTS-C
- Mitochondrial DNA-encoded peptide → insulin sensitivity
- Metabolic inflexibility, fat oxidation
- 5–10mg 2–3×/week
- Emerging research peptide. Strongest evidence for mitochondrial function
- TB-500
- Thymosin beta-4 fragment → cell migration
- Post-injury inflammation, mobility
- 2–5mg 2×/week for 4–6 weeks
- Synergistic with BPC-157 for structural injuries; less studied alone
- Semax
- ACTH analog → dopamine/serotonin modulation
- Focus, cognitive load, neuroprotection
- 200–600 mcg/nostril 1–2×/day
- Intranasal spray
- Best cognitive peptide for sustained focus without stimulant crash
- Selank
- Tuftsin analog → GABAergic anxiolysis
- Stress resilience, anxiety without sedation
- 200–600 mcg/nostril as needed
- Rare anxiolytic that preserves working memory. Underrated for high-pressure periods