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Aging-Specific vs Injury-Specific Models
Much of the published preclinical data for these compounds uses acute injury models in young adult animals. Anti-aging research requires models that specifically capture the biology of aged tissue — aged rodents, aged cell cultures, or accelerated aging models
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- Much of the published preclinical data for these compounds uses acute injury models in young adult animals. Anti-aging research requires models that specifically capture the biology of aged tissue — aged rodents, aged cell cultures, or accelerated aging models. The transition from injury-repair evidence to aging biology evidence is not automatic, and researchers should be cautious about extrapolating too directly between these contexts.